catenin pools meaning in English
连环素集合池
Examples
- Studies revealed that p - catenin dissociated from ccc and translocated into free catenin pool in cytosol after it has been phosphorylated at tyrosine or serine residues , and in this situation , the ccc has been disrupted and cell adhesion function disturbed . a large amount of the free p - catenins in the cytosol can be degraded by the tumor suppressor apc , and the remains translocate into nucleus and bind to transcriptional factor tcf / lef in the nucleus and then promote cell proliferation related gene or anti - apoptosis gene transcription
当-连环蛋白酪氨酸或丝氨酸残基磷酸化后，就与ajs发生解离而游离到细胞浆中，此时细胞的粘附功能也发生障碍，游离到胞浆中的-连环蛋白，一部分被抑癌因子apc降解，一部分则转移到细胞核内，与核内的转录因子tcf lef结合，启动与细胞增殖有关的基因转录。